1. The Supremes' first hit without Diana Ross: "Up the Ladder to the Roof"
2. Billy Joel's 1983 tribute to Christie Brinkley: "Uptown Girl"
3. A hit for the Everly Brothers in 1957, and Simon and Garfunkel in 1982: "Wake Up Little Susie"
4. "Would you like to ride in my beautiful balloon...": "Up-Up And Away"
5. The theme from the movie "An Officer And A Gentleman": "Up Where We Belong"
6. Paula Abdul's first hit, that went to Number One in 1989: "Straight Up"
7. Creedence Clearwater Revival song that mentions the banjo and the big red tree: "Up Around The Bend"
8. A hit for the Drifters in 1963 and (slowed down) for James Taylor in 1979: "Up On The Roof"
9. This was a fluke solo hit for KC in 1984 in the US, but was KC and the Sunshine Band's only Number One hit in the UK in 1983: "Give It Up"
10. Shalamar's hit which was actually a medley of Motown songs: "Uptown Festival"
11. Rolling Stones song that opens up the "Tattoo You" album: "Start Me Up"
12. Neil Sedaka had a hit with this song twice, in two different versions: "Breaking Up Is Hard To Do"
13.Yaz album that includes "Don't Go": "Upstairs At Eric's"
14.In which Bob Marley urges us to "Don't give up the fight!": "Get Up, Stand Up"
15.Diana Ross' 1980 Number One hit, produced by Nile Rogers and Bernard Edwards: "Upside Down"
16.Stevie Wonder's 1966 song that begins with a high trumpet fanfare: "Uptight (Everything's Allright)"
17. The Band song that mentions Lake Charles, Louisiana: "Up On Cripple Creek"

Bonus: REM's first album without drummer Bill Berry" "Up"

Super Bonus: Grateful Dead song in which the first two words of the title are reversed in the lyrics: "Mississippi Half-Step Uptown Toodleloo